What Does the Bible Say About Depression?

"For the Chief Musician. A contemplation by the sons of Korah. As the deer pants for the water brooks, so my soul pants after you, God. My soul thirsts for God, for the living God. When shall I come and appear before God? My tears have been my food day and night, while they continually ask me, “Where is your God?” These things I remember, and pour out my soul within me, how I used to go with the crowd, and led them to God’s house, with the voice of joy and praise, a multitude keeping a holy day. Why are you in despair, my soul? Why are you disturbed within me? Hope in God! For I shall still praise him for the saving help of his presence. My God, my soul is in despair within me. Therefore I remember you from the land of the Jordan, the heights of Hermon, from the hill Mizar. Deep calls to deep at the noise of your waterfalls. All your waves and your billows have swept over me. The LORD will command his loving kindness in the daytime. In the night his song shall be with me: a prayer to the God of my life. I will ask God, my rock, “Why have you forgotten me? Why do I go mourning because of the oppression of the enemy?” As with a sword in my bones, my adversaries reproach me, while they continually ask me, “Where is your God?” Why are you in despair, my soul? Why are you disturbed within me? Hope in God! For I shall still praise him, the saving help of my countenance, and my God."

"I am the man who has seen affliction by the rod of his wrath. He has led me and caused me to walk in darkness, and not in light. Surely he turns his hand against me again and again all day long. He has made my flesh and my skin old. He has broken my bones. He has built against me, and surrounded me with bitterness and hardship. He has made me dwell in dark places, as those who have been long dead. He has walled me about, so that I can’t go out. He has made my chain heavy. Yes, when I cry, and call for help, he shuts out my prayer. He has walled up my ways with cut stone. He has made my paths crooked. He is to me as a bear lying in wait, as a lion in hiding. He has turned away my path, and pulled me in pieces. He has made me desolate. He has bent his bow, and set me as a mark for the arrow. He has caused the shafts of his quiver to enter into my kidneys. I have become a derision to all my people, and their song all day long. He has filled me with bitterness. He has stuffed me with wormwood. He has also broken my teeth with gravel. He has covered me with ashes. You have removed my soul far away from peace. I forgot prosperity. I said, “My strength has perished, along with my expectation from the LORD.” Remember my affliction and my misery, the wormwood and the bitterness. My soul still remembers them, and is bowed down within me. This I recall to my mind; therefore I have hope."

"It is because of the LORD’s loving kindnesses that we are not consumed, because his mercies don’t fail. They are new every morning. Great is your faithfulness. “The LORD is my portion,” says my soul. “Therefore I will hope in him.” The LORD is good to those who wait for him, to the soul who seeks him. It is good that a man should hope and quietly wait for the salvation of the LORD. It is good for a man that he bear the yoke in his youth. Let him sit alone and keep silence, because he has laid it on him. Let him put his mouth in the dust, if it is so that there may be hope. Let him give his cheek to him who strikes him. Let him be filled full of reproach. For the Lord will not cast off forever. For though he causes grief, yet he will have compassion according to the multitude of his loving kindnesses. For he does not afflict willingly, nor grieve the children of men. To crush under foot all the prisoners of the earth, to turn away the right of a man before the face of the Most High, to subvert a man in his cause, the Lord doesn’t approve. Who is he who says, and it comes to pass, when the Lord doesn’t command it? Doesn’t evil and good come out of the mouth of the Most High? Why should a living man complain, a man for the punishment of his sins? Let us search and try our ways, and turn again to the LORD. Let’s lift up our heart with our hands to God in the heavens."

"Now we who are strong ought to bear the weaknesses of the weak, and not to please ourselves. Let each one of us please his neighbor for that which is good, to be building him up. For even Christ didn’t please himself. But, as it is written, “The reproaches of those who reproached you fell on me.” For whatever things were written before were written for our learning, that through perseverance and through encouragement of the Scriptures we might have hope. Now the God of perseverance and of encouragement grant you to be of the same mind with one another according to Christ Jesus, that with one accord you may with one mouth glorify the God and Father of our Lord Jesus Christ. Therefore accept one another, even as Christ also accepted you, to the glory of God. Now I say that Christ has been made a servant of the circumcision for the truth of God, that he might confirm the promises given to the fathers, and that the Gentiles might glorify God for his mercy. As it is written, “Therefore I will give praise to you among the Gentiles and sing to your name.” Again he says, “Rejoice, you Gentiles, with his people.” Again, “Praise the Lord, all you Gentiles! Let all the peoples praise him.” Again, Isaiah says, “There will be the root of Jesse, he who arises to rule over the Gentiles; in him the Gentiles will hope.”"

"Now may the God of hope fill you with all joy and peace in believing, that you may abound in hope in the power of the Holy Spirit. I myself am also persuaded about you, my brothers, that you yourselves are full of goodness, filled with all knowledge, able also to admonish others. But I write the more boldly to you in part as reminding you, because of the grace that was given to me by God, that I should be a servant of Christ Jesus to the Gentiles, serving as a priest of the Good News of God, that the offering up of the Gentiles might be made acceptable, sanctified by the Holy Spirit. I have therefore my boasting in Christ Jesus in things pertaining to God. For I will not dare to speak of any things except those which Christ worked through me for the obedience of the Gentiles, by word and deed, in the power of signs and wonders, in the power of God’s Spirit; so that from Jerusalem and around as far as to Illyricum, I have fully preached the Good News of Christ; yes, making it my aim to preach the Good News, not where Christ was already named, that I might not build on another’s foundation. But, as it is written, “They will see, to whom no news of him came. They who haven’t heard will understand.” Therefore also I was hindered these many times from coming to you, but now, no longer having any place in these regions, and having these many years a longing to come to you,"